Real Radio Northwest breakfast presenters David Ditchfield and Paul Salt, better known as Ditchy and Salty, are being split up and placed elsewhere on the schedule.
The station says a new breakfast team will be announced shortly, along with a new line-up.
The changes come just two months after Programme Director Dave Shearer left the station after being made redundant.
Mark Matthews, who is now the Real Radio Brand Programme Director said: “We will be starting the new year with a fresh new Real Breakfast Show and we will be unveiling the new team very soon. Ditchy and Salty have entertained listeners at breakfast across the north west for 3 ½ years and we thank them for their hard work and commitment to the station.”